Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y

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Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y

A simple, sensitive and rapid spectrophotometric method was developed and validated for the determination of two skeletal muscle relaxants namely, tizanidine hydrochloride (I) and orphenadrine citrate (II) in pharmaceutical formulations. The proposed method is based on the formation of a binary complex between the studied drugs and eosin Y in aqueous buffered medium (pH 3.5). Under the optimum ...

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Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation

Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...

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Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation

Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...

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Extractive Spectrophotometric Determination of Nisoldipine by Ion-pair Complex Formation

Nisoldipine, a 1-4-dihydropyridine drug is determined by the development of simple and sensitive Extractive Spectrophotometric method. In the present study an ion-pair complex of amino derivative of the Nisoldipine with Bromocresol Green Solution in acidic medium is formed with subsequent extraction of the ion-pair complex in Chloroform. Maximum absorption was seen at the wavelength of 418 nm t...

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Spectrophotometric Determination of Chromium . Based on Ion-Pair Formation

A sensitive spectrophotometric method for the determination of trace amounts of chromium(VI) is described. Chromium(VI) forms chlorochromate anion in the presence of acid and chloride ion. The formed anion is extracted in toluene as ion-pair with a cationic dye rhodamine 6G. At 535 nlll absorption maximum molar absorptivity is 2x104 I mol-I em-I. The colour is stable for 4 h and the system obey...

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ژورنال

عنوان ژورنال: Chemistry Central Journal

سال: 2011

ISSN: 1752-153X

DOI: 10.1186/1752-153x-5-60